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Epigenetic age acceleration predicts cancer, cardiovascular, and all-cause mortality in a German case cohort

BACKGROUND: Previous studies have developed models predicting methylation age from DNA methylation in blood and other tissues (epigenetic clock) and suggested the difference between DNA methylation and chronological ages as a marker of healthy aging. The goal of this study was to confirm and expand...

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Detalles Bibliográficos
Autores principales: Perna, Laura, Zhang, Yan, Mons, Ute, Holleczek, Bernd, Saum, Kai-Uwe, Brenner, Hermann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891876/
https://www.ncbi.nlm.nih.gov/pubmed/27274774
http://dx.doi.org/10.1186/s13148-016-0228-z