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Epigenetic age acceleration predicts cancer, cardiovascular, and all-cause mortality in a German case cohort
BACKGROUND: Previous studies have developed models predicting methylation age from DNA methylation in blood and other tissues (epigenetic clock) and suggested the difference between DNA methylation and chronological ages as a marker of healthy aging. The goal of this study was to confirm and expand...
Autores principales: | Perna, Laura, Zhang, Yan, Mons, Ute, Holleczek, Bernd, Saum, Kai-Uwe, Brenner, Hermann |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891876/ https://www.ncbi.nlm.nih.gov/pubmed/27274774 http://dx.doi.org/10.1186/s13148-016-0228-z |
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