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Antibodies directed against endogenous and exogenous citrullinated antigens pre-date the onset of rheumatoid arthritis
BACKGROUND: Anti-citrullinated-peptide antibodies (ACPA) have been detected in individuals with developing rheumatoid arthritis (RA) before the onset of symptom, with an initially limited spectrum of reactivities that gradually broadens. The aim was to analyze the evolution of ACPA response pre-dati...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891920/ https://www.ncbi.nlm.nih.gov/pubmed/27255888 http://dx.doi.org/10.1186/s13075-016-1031-0 |