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Antibodies directed against endogenous and exogenous citrullinated antigens pre-date the onset of rheumatoid arthritis

BACKGROUND: Anti-citrullinated-peptide antibodies (ACPA) have been detected in individuals with developing rheumatoid arthritis (RA) before the onset of symptom, with an initially limited spectrum of reactivities that gradually broadens. The aim was to analyze the evolution of ACPA response pre-dati...

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Detalles Bibliográficos
Autores principales: Johansson, Linda, Pratesi, Federico, Brink, Mikael, Ärlestig, Lisbeth, D’Amato, Claudia, Bartaloni, Debora, Migliorini, Paola, Rantapää-Dahlqvist, Solbritt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891920/
https://www.ncbi.nlm.nih.gov/pubmed/27255888
http://dx.doi.org/10.1186/s13075-016-1031-0