Intrathecal T‐cell clonal expansions in patients with multiple sclerosis

OBJECTIVE: Analysis of the T‐cell receptor (TCR) repertoire in the cerebrospinal fluid (CSF) of patients with multiple sclerosis (MS) can reveal antigen‐specific immune responses potentially implicated in the disease process. We applied a new unbiased deep‐sequencing method for TCR repertoire analys...

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Detalles Bibliográficos
Autores principales: de Paula Alves Sousa, Alessandra, Johnson, Kory R., Nicholas, Richard, Darko, Sam, Price, David A., Douek, Daniel C., Jacobson, Steven, Muraro, Paolo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891996/
https://www.ncbi.nlm.nih.gov/pubmed/27547770
http://dx.doi.org/10.1002/acn3.310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891996/
https://www.ncbi.nlm.nih.gov/pubmed/27547770
http://dx.doi.org/10.1002/acn3.310

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