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Intrathecal T‐cell clonal expansions in patients with multiple sclerosis
OBJECTIVE: Analysis of the T‐cell receptor (TCR) repertoire in the cerebrospinal fluid (CSF) of patients with multiple sclerosis (MS) can reveal antigen‐specific immune responses potentially implicated in the disease process. We applied a new unbiased deep‐sequencing method for TCR repertoire analys...
Autores principales: | de Paula Alves Sousa, Alessandra, Johnson, Kory R., Nicholas, Richard, Darko, Sam, Price, David A., Douek, Daniel C., Jacobson, Steven, Muraro, Paolo A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891996/ https://www.ncbi.nlm.nih.gov/pubmed/27547770 http://dx.doi.org/10.1002/acn3.310 |
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