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Nmnat1 protects neuronal function without altering phospho‐tau pathology in a mouse model of tauopathy

OBJECTIVE: The nicotinamide‐nucleotide adenylyltransferase protein Nmnat1 is a potent inhibitor of axonal degeneration in models of acute axonal injury. Hyperphosphorylation and aggregation of the microtubule‐associated protein Tau are associated with neurodegeneration in Alzheimer's Disease an...

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Detalles Bibliográficos
Autores principales:	Musiek, Erik S., Xiong, David D., Patel, Tirth, Sasaki, Yo, Wang, Yinong, Bauer, Adam Q., Singh, Risham, Finn, Samantha L., Culver, Joseph P., Milbrandt, Jeffrey, Holtzman, David M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891997/ https://www.ncbi.nlm.nih.gov/pubmed/27547771 http://dx.doi.org/10.1002/acn3.308

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