Development of an Ad5H3 Chimera Using the “Antigen Capsid-Incorporation” Strategy for an Alternative Vaccination Approach

BACKGROUND: Adenovirus type 5 (Ad5) achieved success as a conventional transgene vaccine vector in preclinical trials, however; achieved poor efficiency in some of the clinical trials, due to the major hurdle associated with Ad5 pre-existing immunity (PEI) in the majority of the human population. OB...

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Detalles Bibliográficos
Autores principales: Gu, Linlin, Icyuz, Mert, Krendelchtchikova, Valentina, Krendelchtchikov, Alexandre, Johnston, Alison E., Matthews, Qiana L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892130/
https://www.ncbi.nlm.nih.gov/pubmed/27335626
http://dx.doi.org/10.2174/1874357901610010010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892130/
https://www.ncbi.nlm.nih.gov/pubmed/27335626
http://dx.doi.org/10.2174/1874357901610010010

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