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Restoration of Retarded Influenza Virus-specific Immunoglobulin Class Switch in Aged Mice
OBJECTIVE: The declined immune response to infection causes significant higher morbidity and mortality in aging in spite of the coexisted hyperimmunoglobulinemia (HIG). This study is to reveal the cellular basis of HIG and mechanism of weakened HA-specific IgG response in aged mice and to test cell...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892186/ https://www.ncbi.nlm.nih.gov/pubmed/27274907 http://dx.doi.org/10.4172/2155-9899.1000403 |