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Synthesis, activity, and docking study of phenylthiazole acids as potential agonists of PPARγ

Peroxisome proliferator-activated receptor gamma (PPARγ) is a ligand-mediated transcription factor playing key roles in glucose and lipid homeostasis, and PPARγ ligands possess therapeutic potential in these as well as other areas. In this study, a series of phenylthiazole acids have been synthesize...

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Detalles Bibliográficos
Autores principales: Ma, Liang, Wang, Taijin, Shi, Min, Ye, Haoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892293/
https://www.ncbi.nlm.nih.gov/pubmed/27313447
http://dx.doi.org/10.2147/DDDT.S106406