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Contribution of Somatic and Dendritic SK Channels in the Firing Rate of Deep Cerebellar Nuclei: Implication in Cerebellar Ataxia

INTRODUCTION: Loss of inhibitory output from Purkinje cells leads to hyperexcitability of the Deep Cerebellar Nuclei (DCN), which results in cerebellar ataxia. Also, inhibition of small-conductance calcium-activated potassium (SK) channel increases firing rate of DCN, which could cause cerebellar at...

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Detalles Bibliográficos
Autores principales: Abbasi, Samira, Abbasi, Ataollah, Sarbaz, Yashar, Shahabi, Parviz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Neuroscience Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892332/
https://www.ncbi.nlm.nih.gov/pubmed/27303600