Ex vivo mammalian prions are formed of paired double helical prion protein fibrils

Mammalian prions are hypothesized to be fibrillar or amyloid forms of prion protein (PrP), but structures observed to date have not been definitively correlated with infectivity and the three-dimensional structure of infectious prions has remained obscure. Recently, we developed novel methods to obt...

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Detalles Bibliográficos
Autores principales: Terry, Cassandra, Wenborn, Adam, Gros, Nathalie, Sells, Jessica, Joiner, Susan, Hosszu, Laszlo L. P., Tattum, M. Howard, Panico, Silvia, Clare, Daniel K., Collinge, John, Saibil, Helen R., Wadsworth, Jonathan D. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892434/
https://www.ncbi.nlm.nih.gov/pubmed/27249641
http://dx.doi.org/10.1098/rsob.160035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892434/
https://www.ncbi.nlm.nih.gov/pubmed/27249641
http://dx.doi.org/10.1098/rsob.160035

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