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Structure of astrotactin-2: a conserved vertebrate-specific and perforin-like membrane protein involved in neuronal development

The vertebrate-specific proteins astrotactin-1 and 2 (ASTN-1 and ASTN-2) are integral membrane perforin-like proteins known to play critical roles in neurodevelopment, while ASTN-2 has been linked to the planar cell polarity pathway in hair cells. Genetic variations associated with them are linked t...

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Detalles Bibliográficos
Autores principales: Ni, Tao, Harlos, Karl, Gilbert, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892435/
https://www.ncbi.nlm.nih.gov/pubmed/27249642
http://dx.doi.org/10.1098/rsob.160053