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Structure of astrotactin-2: a conserved vertebrate-specific and perforin-like membrane protein involved in neuronal development
The vertebrate-specific proteins astrotactin-1 and 2 (ASTN-1 and ASTN-2) are integral membrane perforin-like proteins known to play critical roles in neurodevelopment, while ASTN-2 has been linked to the planar cell polarity pathway in hair cells. Genetic variations associated with them are linked t...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892435/ https://www.ncbi.nlm.nih.gov/pubmed/27249642 http://dx.doi.org/10.1098/rsob.160053 |