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Immunoadjuvant Properties of the Rho Activating Factor CNF1 in Prophylactic and Curative Vaccination against Leishmania infantum

There is a need to develop new effective immunoadjuvants for prophylactic or therapeutic vaccines against intracellular pathogens. The activation of Rho GTPases by bacterial cytotoxic necrotizing factor 1 (CNF1) elicits humoral protective responses against protein antigens. Here, we set out to inves...

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Detalles Bibliográficos
Autores principales: Michel, Grégory, Ferrua, Bernard, Munro, Patrick, Boyer, Laurent, Mathal, Nassim, Gillet, Daniel, Marty, Pierre, Lemichez, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892475/
https://www.ncbi.nlm.nih.gov/pubmed/27257862
http://dx.doi.org/10.1371/journal.pone.0156363