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The Third Intron of the Interferon Regulatory Factor-8 Is an Initiator of Repressed Chromatin Restricting Its Expression in Non-Immune Cells

Interferon Regulatory Factor-8 (IRF-8) serves as a key factor in the hierarchical differentiation towards monocyte/dendritic cell lineages. While much insight has been accumulated into the mechanisms essential for its hematopoietic specific expression, the mode of restricting IRF-8 expression in non...

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Detalles Bibliográficos
Autores principales: Khateb, Mamduh, Fourier, Nitsan, Barnea-Yizhar, Ofer, Ram, Sigal, Kovalev, Ekaterina, Azriel, Aviva, Rand, Ulfert, Nakayama, Manabu, Hauser, Hansjörg, Gepstein, Lior, Levi, Ben-Zion
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892516/
https://www.ncbi.nlm.nih.gov/pubmed/27257682
http://dx.doi.org/10.1371/journal.pone.0156812