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Analysis of Risk Alleles and Complement Activation Levels in Familial and Non-Familial Age-Related Macular Degeneration

AIMS: Age-related macular degeneration (AMD) is a multifactorial disease, in which complement-mediated inflammation plays a pivotal role. A positive family history is an important risk factor for developing AMD. Certain lifestyle factors are shown to be significantly associated with AMD in non-famil...

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Detalles Bibliográficos
Autores principales: Saksens, Nicole T. M., Lechanteur, Yara T. E., Verbakel, Sanne K., Groenewoud, Joannes M. M., Daha, Mohamed R., Schick, Tina, Fauser, Sascha, Boon, Camiel J. F., Hoyng, Carel B., den Hollander, Anneke I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892537/
https://www.ncbi.nlm.nih.gov/pubmed/27258093
http://dx.doi.org/10.1371/journal.pone.0144367