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Discovery and Characterization of Phage Display-Derived Human Monoclonal Antibodies against RSV F Glycoprotein

Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infection in infants, the elderly and in immunosuppressed populations. The vast majority of neutralizing antibodies isolated from human subjects target the RSV fusion (F) glycoprotein, making it an attractive target for...

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Detalles Bibliográficos
Autores principales: Chen, Zhifeng, Zhang, Lan, Tang, Aimin, Callahan, Cheryl, Pristatsky, Pavlo, Swoyer, Ryan, Cejas, Pedro, Nahas, Debbie, Galli, Jennifer, Cosmi, Scott, DiStefano, Daniel, Hoang, Van M., Bett, Andrew, Casimiro, Danilo, Vora, Kalpit A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892554/
https://www.ncbi.nlm.nih.gov/pubmed/27258388
http://dx.doi.org/10.1371/journal.pone.0156798