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Discovery and Characterization of Phage Display-Derived Human Monoclonal Antibodies against RSV F Glycoprotein
Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infection in infants, the elderly and in immunosuppressed populations. The vast majority of neutralizing antibodies isolated from human subjects target the RSV fusion (F) glycoprotein, making it an attractive target for...
Autores principales: | Chen, Zhifeng, Zhang, Lan, Tang, Aimin, Callahan, Cheryl, Pristatsky, Pavlo, Swoyer, Ryan, Cejas, Pedro, Nahas, Debbie, Galli, Jennifer, Cosmi, Scott, DiStefano, Daniel, Hoang, Van M., Bett, Andrew, Casimiro, Danilo, Vora, Kalpit A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892554/ https://www.ncbi.nlm.nih.gov/pubmed/27258388 http://dx.doi.org/10.1371/journal.pone.0156798 |
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