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Bending-Twisting Motions and Main Interactions in Nucleoplasmin Nuclear Import

Alpha solenoid proteins play a key role in regulating the classical nuclear import pathway, recognizing a target protein and transporting it into the nucleus. Importin-α (Impα) is the solenoid responsible for cargo protein recognition, and it has been extensively studied by X-ray crystallography to...

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Detalles Bibliográficos
Autores principales: Geraldo, Marcos Tadeu, Takeda, Agnes Alessandra Sekijima, Braz, Antônio Sérgio Kimus, Lemke, Ney
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892583/
https://www.ncbi.nlm.nih.gov/pubmed/27258022
http://dx.doi.org/10.1371/journal.pone.0157162