sFlt Multivalent Conjugates Inhibit Angiogenesis and Improve Half-Life In Vivo

Current anti-VEGF drugs for patients with diabetic retinopathy suffer from short residence time in the vitreous of the eye. In order to maintain biologically effective doses of drug for inhibiting retinal neovascularization, patients are required to receive regular monthly injections of drug, which...

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Detalles Bibliográficos
Autores principales: Altiok, Eda I., Browne, Shane, Khuc, Emily, Moran, Elizabeth P., Qiu, Fangfang, Zhou, Kelu, Santiago-Ortiz, Jorge L., Ma, Jian-xing, Chan, Matilda F., Healy, Kevin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892585/
https://www.ncbi.nlm.nih.gov/pubmed/27257918
http://dx.doi.org/10.1371/journal.pone.0155990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892585/
https://www.ncbi.nlm.nih.gov/pubmed/27257918
http://dx.doi.org/10.1371/journal.pone.0155990

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