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sFlt Multivalent Conjugates Inhibit Angiogenesis and Improve Half-Life In Vivo
Current anti-VEGF drugs for patients with diabetic retinopathy suffer from short residence time in the vitreous of the eye. In order to maintain biologically effective doses of drug for inhibiting retinal neovascularization, patients are required to receive regular monthly injections of drug, which...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892585/ https://www.ncbi.nlm.nih.gov/pubmed/27257918 http://dx.doi.org/10.1371/journal.pone.0155990 |