Identification of New Mutations at the PCNA Subunit Interface that Block Translesion Synthesis

Proliferating cell nuclear antigen (PCNA) plays an essential role in DNA replication and repair by interacting with a large number of proteins involved in these processes. Two amino acid substitutions in PCNA, both located at the subunit interface, have previously been shown to block translesion syn...

Descripción completa

Detalles Bibliográficos
Autores principales: Kondratick, Christine M., Boehm, Elizabeth M., Dieckman, Lynne M., Powers, Kyle T., Sanchez, Julio C., Mueting, Samuel R., Washington, M. Todd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892588/
https://www.ncbi.nlm.nih.gov/pubmed/27258147
http://dx.doi.org/10.1371/journal.pone.0157023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892588/
https://www.ncbi.nlm.nih.gov/pubmed/27258147
http://dx.doi.org/10.1371/journal.pone.0157023

Ejemplares similares