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Identification of New Mutations at the PCNA Subunit Interface that Block Translesion Synthesis
Proliferating cell nuclear antigen (PCNA) plays an essential role in DNA replication and repair by interacting with a large number of proteins involved in these processes. Two amino acid substitutions in PCNA, both located at the subunit interface, have previously been shown to block translesion syn...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892588/ https://www.ncbi.nlm.nih.gov/pubmed/27258147 http://dx.doi.org/10.1371/journal.pone.0157023 |