Prevalence and Prognostic Role of BRCA1/2 Variants in Unselected Chinese Breast Cancer Patients

BACKGROUND: The prevalence of BRCA1/2 variants in Chinese breast cancer patients varies among studies. Germline or somatic BRCA1/2 mutations are associated with sensitivity to poly(ADP-ribose) polymerase-1 inhibitors and DNA-damaging agents. We aimed to investigate the distribution of both somatic a...

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Detalles Bibliográficos
Autores principales: Zhong, Xiaorong, Dong, Zhengwei, Dong, Hua, Li, Jiayuan, Peng, Zuxiang, Deng, Ling, Zhu, Xuehua, Sun, Yun, Lu, Xuesong, Shen, Fuxiao, Su, Xinying, Zhang, Liying, Gu, Yi, Zheng, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892623/
https://www.ncbi.nlm.nih.gov/pubmed/27257965
http://dx.doi.org/10.1371/journal.pone.0156789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892623/
https://www.ncbi.nlm.nih.gov/pubmed/27257965
http://dx.doi.org/10.1371/journal.pone.0156789

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