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Conessine Interferes with Oxidative Stress-Induced C2C12 Myoblast Cell Death through Inhibition of Autophagic Flux

Conessine, a steroidal alkaloid isolated from Holarrhena floribunda, has anti-malarial activity and interacts with the histamine H3 receptor. However, the cellular effects of conessine are poorly understood. Accordingly, we evaluated the involvement of conessine in the regulation of autophagy. We se...

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Detalles Bibliográficos
Autores principales: Kim, Hyunju, Lee, Kang Il, Jang, Minsu, Namkoong, Sim, Park, Rackhyun, Ju, Hyunwoo, Choi, Inho, Oh, Won Keun, Park, Junsoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892631/
https://www.ncbi.nlm.nih.gov/pubmed/27257813
http://dx.doi.org/10.1371/journal.pone.0157096