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Conessine Interferes with Oxidative Stress-Induced C2C12 Myoblast Cell Death through Inhibition of Autophagic Flux
Conessine, a steroidal alkaloid isolated from Holarrhena floribunda, has anti-malarial activity and interacts with the histamine H3 receptor. However, the cellular effects of conessine are poorly understood. Accordingly, we evaluated the involvement of conessine in the regulation of autophagy. We se...
Autores principales: | Kim, Hyunju, Lee, Kang Il, Jang, Minsu, Namkoong, Sim, Park, Rackhyun, Ju, Hyunwoo, Choi, Inho, Oh, Won Keun, Park, Junsoo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892631/ https://www.ncbi.nlm.nih.gov/pubmed/27257813 http://dx.doi.org/10.1371/journal.pone.0157096 |
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