Novel Plasminogen Activator Inhibitor-1 Inhibitors Prevent Diabetic Kidney Injury in a Mouse Model

Diabetic nephropathy is the leading cause of end-stage renal disease worldwide, but no effective therapeutic strategy is available. Because plasminogen activator inhibitor-1 (PAI-1) is increasingly recognized as a key factor in extracellular matrix (ECM) accumulation in diabetic nephropathy, this st...

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Detalles Bibliográficos
Autores principales: Jeong, Bo Yeong, Uddin, Md Jamal, Park, Jong Hee, Lee, Jung Hwa, Lee, Hi Bahl, Miyata, Toshio, Ha, Hunjoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892642/
https://www.ncbi.nlm.nih.gov/pubmed/27258009
http://dx.doi.org/10.1371/journal.pone.0157012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892642/
https://www.ncbi.nlm.nih.gov/pubmed/27258009
http://dx.doi.org/10.1371/journal.pone.0157012

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