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Anti-ganglioside antibodies are removed from circulation in mice by neuronal endocytosis

See van Doorn and Jacobs (doi:10.1093/brain/aww078) for a scientific commentary on this article.   In axonal forms of Guillain-Barré syndrome, anti-ganglioside antibodies bind gangliosides on nerve surfaces, thereby causing injury through complement activation and immune cell recruitment. Why some n...

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Detalles Bibliográficos
Autores principales: Cunningham, Madeleine E., McGonigal, Rhona, Meehan, Gavin R., Barrie, Jennifer A., Yao, Denggao, Halstead, Susan K., Willison, Hugh J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892750/
https://www.ncbi.nlm.nih.gov/pubmed/27017187
http://dx.doi.org/10.1093/brain/aww056