Development of paroxysmal nocturnal hemoglobinuria in CALR-positive myeloproliferative neoplasm

Paroxysmal nocturnal hemoglobinuria (PNH), a disease characterized by intravascular hemolysis, thrombosis, and bone marrow failure, is associated with mutations in the PIG-A gene, resulting in a deficiency of glycosylphosphatidylinositol-anchored proteins. Many hypotheses have been posed as to wheth...

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Detalles Bibliográficos
Autores principales: Fraiman, Yarden S, Cuka, Nathan, Batista, Denise, Vuica-Ross, Milena, Moliterno, Alison R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892839/
https://www.ncbi.nlm.nih.gov/pubmed/27313483
http://dx.doi.org/10.2147/JBM.S103473

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