ANT2 shRNA downregulates miR-19a and miR-96 through the PI3K/Akt pathway and suppresses tumor growth in hepatocellular carcinoma cells

MicroRNAs (miRNAs) are negative regulators of gene expression, and miRNA deregulation is found in various tumors. We previously reported that suppression of adenine nucleotide translocase 2 (ANT2) by short hairpin RNA (shRNA) inhibits hepatocellular carcinoma (HCC) development by rescuing miR-636 ex...

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Detalles Bibliográficos
Autores principales: Baik, Seung Hyun, Lee, Jongkuen, Lee, Yeong-Shin, Jang, Ji-Young, Kim, Chul-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892878/
https://www.ncbi.nlm.nih.gov/pubmed/27012708
http://dx.doi.org/10.1038/emm.2015.126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892878/
https://www.ncbi.nlm.nih.gov/pubmed/27012708
http://dx.doi.org/10.1038/emm.2015.126

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