STEP signaling pathway mediates psychomotor stimulation and morphine withdrawal symptoms, but not for reward, analgesia and tolerance

Striatal-enriched protein tyrosine phosphatase (STEP) is abundantly expressed in the striatum, which strongly expresses dopamine and opioid receptors and mediates the effects of many drugs of abuse. However, little is known about the role of STEP in opioid receptor function. In the present study, we...

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Detalles Bibliográficos
Autores principales: Kim, Yoon-Jung, Kang, Young, Park, Hye-Yeon, Lee, Jae-Ran, Yu, Dae-Yeul, Murata, Takuya, Gondo, Yoichi, Hwang, Jung Hwan, Kim, Yong-Hoon, Lee, Chul-Ho, Rhee, Myungchull, Han, Pyung-Lim, Chung, Bong-Hyun, Lee, Hyun-Jun, Kim, Kyoung-Shim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892880/
https://www.ncbi.nlm.nih.gov/pubmed/26915673
http://dx.doi.org/10.1038/emm.2016.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892880/
https://www.ncbi.nlm.nih.gov/pubmed/26915673
http://dx.doi.org/10.1038/emm.2016.1

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