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Dual functions of a small regulatory subunit in the mitochondrial calcium uniporter complex

Mitochondrial Ca(2+) uptake, a process crucial for bioenergetics and Ca(2+) signaling, is catalyzed by the mitochondrial calcium uniporter. The uniporter is a multi-subunit Ca(2+)-activated Ca(2+) channel, with the Ca(2+) pore formed by the MCU protein and Ca(2+)-dependent activation mediated by MIC...

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Detalles Bibliográficos
Autores principales: Tsai, Ming-Feng, Phillips, Charles B, Ranaghan, Matthew, Tsai, Chen-Wei, Wu, Yujiao, Williams, Carole, Miller, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892889/
https://www.ncbi.nlm.nih.gov/pubmed/27099988
http://dx.doi.org/10.7554/eLife.15545