Targeting Myc in KSHV-associated primary effusion lymphoma with BET bromodomain inhibitors

Primary effusion lymphoma (PEL) is an aggressive form of non-Hodgkin's B cell lymphoma associated with infection by Kaposi's sarcoma associated herpesvirus (KSHV). (+)-JQ1 and I-BET151 are two recently described novel small molecule inhibitors of BET bromodomain chromatin-associated protei...

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Detalles Bibliográficos
Autores principales: Tolani, Bhairavi, Gopalakrishnan, Ramakrishnan, Punj, Vasu, Matta, Hittu, Chaudhary, Preet M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892892/
https://www.ncbi.nlm.nih.gov/pubmed/23792448
http://dx.doi.org/10.1038/onc.2013.242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892892/
https://www.ncbi.nlm.nih.gov/pubmed/23792448
http://dx.doi.org/10.1038/onc.2013.242

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