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Targeting Myc in KSHV-associated primary effusion lymphoma with BET bromodomain inhibitors
Primary effusion lymphoma (PEL) is an aggressive form of non-Hodgkin's B cell lymphoma associated with infection by Kaposi's sarcoma associated herpesvirus (KSHV). (+)-JQ1 and I-BET151 are two recently described novel small molecule inhibitors of BET bromodomain chromatin-associated protei...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892892/ https://www.ncbi.nlm.nih.gov/pubmed/23792448 http://dx.doi.org/10.1038/onc.2013.242 |