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The autoimmunity-associated gene RGS1 affects the frequency of T follicular helper cells
RGS1 (regulator of G-protein signaling 1) has been associated with multiple autoimmune disorders including type 1 diabetes. RGS1 desensitizes the chemokine receptors CCR7 and CXCR4 that are critical to the localization of T and B cells in lymphoid organs. To explore how RGS1 variation contributes to...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892947/ https://www.ncbi.nlm.nih.gov/pubmed/27029527 http://dx.doi.org/10.1038/gene.2016.16 |