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Ischemic A/D transition of mitochondrial complex I and its role in ROS generation()

Mitochondrial complex I (NADH:ubiquinone oxidoreductase) is a key enzyme in cellular energy metabolism and provides approximately 40% of the proton-motive force that is utilized during mitochondrial ATP production. The dysregulation of complex I function – either genetically, pharmacologically, or m...

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Detalles Bibliográficos
Autores principales: Dröse, Stefan, Stepanova, Anna, Galkin, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893024/
https://www.ncbi.nlm.nih.gov/pubmed/26777588
http://dx.doi.org/10.1016/j.bbabio.2015.12.013