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Processing and transcriptome expansion at the mRNA 3′ end in health and disease: finding the right end

The human transcriptome is highly dynamic, with each cell type, tissue, and organ system expressing an ensemble of transcript isoforms that give rise to considerable diversity. Apart from alternative splicing affecting the “body” of the transcripts, extensive transcriptome diversification occurs at...

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Detalles Bibliográficos
Autores principales: Ogorodnikov, Anton, Kargapolova, Yulia, Danckwardt, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893057/
https://www.ncbi.nlm.nih.gov/pubmed/27220521
http://dx.doi.org/10.1007/s00424-016-1828-3