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Crystal structure of Porphyromonas gingivalis peptidylarginine deiminase: implications for autoimmunity in rheumatoid arthritis

BACKGROUND: Periodontitis (PD) is a known risk factor for rheumatoid arthritis (RA) and there is increasing evidence that the link between the two diseases is due to citrullination by the unique bacterial peptidylarginine deiminase (PAD) enzyme expressed by periodontal pathogen Pophyromonas gingival...

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Detalles Bibliográficos
Autores principales: Montgomery, Anna B, Kopec, Jolanta, Shrestha, Leela, Thezenas, Marie-Laetitia, Burgess-Brown, Nicola A, Fischer, Roman, Yue, Wyatt W, Venables, Patrick J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893104/
https://www.ncbi.nlm.nih.gov/pubmed/26209657
http://dx.doi.org/10.1136/annrheumdis-2015-207656