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Neutrophil microvesicles resolve gout by inhibiting C5a-mediated priming of the inflammasome
OBJECTIVES: Gout is a highly inflammatory but self-limiting joint disease induced by the precipitation of monosodium urate (MSU) crystals. While it is well established that inflammasome activation by MSU mediates acute inflammation, little is known about the mechanism controlling its spontaneous res...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BMJ Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893114/ https://www.ncbi.nlm.nih.gov/pubmed/26245757 http://dx.doi.org/10.1136/annrheumdis-2015-207338 |