Increased functional connectivity common to symptomatic amyotrophic lateral sclerosis and those at genetic risk

OBJECTIVE: To discern presymptomatic changes in brain structure or function using advanced MRI in carriers of mutations predisposing to amyotrophic lateral sclerosis (ALS). METHODS: T1-weighted, diffusion weighted and resting state functional MRI data were acquired at 3 T for 12 asymptomatic mutatio...

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Detalles Bibliográficos
Autores principales: Menke, Ricarda A L, Proudfoot, Malcolm, Wuu, Joanne, Andersen, Peter M, Talbot, Kevin, Benatar, Michael, Turner, Martin R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Neurodegeneration
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893149/
https://www.ncbi.nlm.nih.gov/pubmed/26733601
http://dx.doi.org/10.1136/jnnp-2015-311945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893149/
https://www.ncbi.nlm.nih.gov/pubmed/26733601
http://dx.doi.org/10.1136/jnnp-2015-311945

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