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The Dynamic Localization of Cytoplasmic Dynein in Neurons Is Driven by Kinesin-1

Cytoplasmic dynein, the major motor driving retrograde axonal transport, must be actively localized to axon terminals. This localization is critical as dynein powers essential retrograde trafficking events required for neuronal survival, such as neurotrophic signaling. Here, we demonstrate that the...

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Detalles Bibliográficos
Autores principales: Twelvetrees, Alison E., Pernigo, Stefano, Sanger, Anneri, Guedes-Dias, Pedro, Schiavo, Giampietro, Steiner, Roberto A., Dodding, Mark P., Holzbaur, Erika L.F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893161/
https://www.ncbi.nlm.nih.gov/pubmed/27210554
http://dx.doi.org/10.1016/j.neuron.2016.04.046