Cargando…

RNF8 promotes epithelial-mesenchymal transition of breast cancer cells

BACKGROUND: Epithelial-mesenchymal transition (EMT) is a crucial step for solid tumor progression and plays an important role in cancer invasion and metastasis. RNF8 is an ubiquitin E3 ligase with RING domain, and plays essential roles in DNA damage response and cell cycle regulation. However the ro...

Descripción completa

Detalles Bibliográficos
Autores principales: Kuang, Jingyu, Li, Li, Guo, Limei, Su, Yanrong, Wang, Yuxuan, Xu, Yongjie, Wang, Xiaozhen, Meng, Shucong, Lei, Liandi, Xu, Luzheng, Shao, Genze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893263/
https://www.ncbi.nlm.nih.gov/pubmed/27259701
http://dx.doi.org/10.1186/s13046-016-0363-6