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Inhibition of Notch 1 receptor influenced the differentiation of Lin-CD45RA-dendritic cell precursors within ovarian carcinoma microenvironment

BACKGROUND: Previous evidence suggested that the differentiation of Lin-CD45RA-DC precursors were prior to plasmcytoid dendritic cells (pDCs) than myeloid dendritic cells (mDCs) within ovarian cancer microenvironment. However, the mechanism is still unclear. Therefore, we investigated the function o...

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Detalles Bibliográficos
Autores principales: Qian, Xue-qian, Chen, Li-li, Cheng, Qi, Tian, Yang, Luo, Xiao-feng, Wan, Xiao-yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893273/
https://www.ncbi.nlm.nih.gov/pubmed/27259477
http://dx.doi.org/10.1186/s12865-016-0150-3