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A functional microRNA library screen reveals miR-410 as a novel anti-apoptotic regulator of cholangiocarcinoma

BACKGROUND: Cholangiocarcinoma is characterized by late diagnosis and a poor survival rate. MicroRNAs have been involved in the pathogenesis of different cancer types, including cholangiocarcinoma. Our aim was to identify novel microRNAs regulating cholangiocarcinoma cell growth in vitro and in vivo...

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Detalles Bibliográficos
Autores principales: Palumbo, Tiziana, Poultsides, George A., Kouraklis, Grigorios, Liakakos, Theodore, Drakaki, Alexandra, Peros, George, Hatziapostolou, Maria, Iliopoulos, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893280/
https://www.ncbi.nlm.nih.gov/pubmed/27259577
http://dx.doi.org/10.1186/s12885-016-2384-0