Comprehensive analysis of promoter-proximal RNA polymerase II pausing across mammalian cell types

BACKGROUND: For many genes, RNA polymerase II stably pauses before transitioning to productive elongation. Although polymerase II pausing has been shown to be a mechanism for regulating transcriptional activation, the extent to which it is involved in control of mammalian gene expression and its rel...

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Detalles Bibliográficos
Autores principales: Day, Daniel S., Zhang, Bing, Stevens, Sean M., Ferrari, Francesco, Larschan, Erica N., Park, Peter J., Pu, William T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893286/
https://www.ncbi.nlm.nih.gov/pubmed/27259512
http://dx.doi.org/10.1186/s13059-016-0984-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893286/
https://www.ncbi.nlm.nih.gov/pubmed/27259512
http://dx.doi.org/10.1186/s13059-016-0984-2

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