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Loss of AP-2delta reduces retinal ganglion cell numbers and axonal projections to the superior colliculus
BACKGROUND: AP-2δ is the most divergent member of the Activating Protein-2 (TFAP2) family of transcription factors. AP-2δ is restricted to specific regions of the CNS, including a subset of ganglion cells in the retina. Retinal ganglion cells (RGCs), the only output neurons of the retina, are respon...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893287/ https://www.ncbi.nlm.nih.gov/pubmed/27259519 http://dx.doi.org/10.1186/s13041-016-0244-0 |