Loss of AP-2delta reduces retinal ganglion cell numbers and axonal projections to the superior colliculus

BACKGROUND: AP-2δ is the most divergent member of the Activating Protein-2 (TFAP2) family of transcription factors. AP-2δ is restricted to specific regions of the CNS, including a subset of ganglion cells in the retina. Retinal ganglion cells (RGCs), the only output neurons of the retina, are respon...

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Detalles Bibliográficos
Autores principales: Li, Xiaodong, Gaillard, Frédéric, Monckton, Elizabeth A., Glubrecht, Darryl D., Persad, Amit R. L., Moser, Markus, Sauvé, Yves, Godbout, Roseline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893287/
https://www.ncbi.nlm.nih.gov/pubmed/27259519
http://dx.doi.org/10.1186/s13041-016-0244-0

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