Synthetic long non-coding RNAs [SINEUPs] rescue defective gene expression in vivo

Non-coding RNAs provide additional regulatory layers to gene expression as well as the potential to being exploited as therapeutic tools. Non-coding RNA-based therapeutic approaches have been attempted in dominant diseases, however their use for treatment of genetic diseases caused by insufficient g...

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Detalles Bibliográficos
Autores principales: Indrieri, Alessia, Grimaldi, Claudia, Zucchelli, Silvia, Tammaro, Roberta, Gustincich, Stefano, Franco, Brunella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893607/
https://www.ncbi.nlm.nih.gov/pubmed/27265476
http://dx.doi.org/10.1038/srep27315

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893607/
https://www.ncbi.nlm.nih.gov/pubmed/27265476
http://dx.doi.org/10.1038/srep27315

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