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Gain of BDNF Function in Engrafted Neural Stem Cells Promotes the Therapeutic Potential for Alzheimer’s Disease

Stem cell-based therapy is a potential treatment for neurodegenerative diseases, but its application to Alzheimer’s disease (AD) remains limited. Brain-derived neurotrophic factor (BDNF) is critical in the pathogenesis and treatment of AD. Here, we present a novel therapeutic approach for AD treatme...

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Detalles Bibliográficos
Autores principales: Wu, Cheng-Chun, Lien, Cheng-Chang, Hou, Wen-Hsien, Chiang, Po-Min, Tsai, Kuen-Jer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893631/
https://www.ncbi.nlm.nih.gov/pubmed/27264956
http://dx.doi.org/10.1038/srep27358