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Polymer-DNA Nanoparticle-Induced CXCR4 Overexpression Improves Stem Cell Engraftment and Tissue Regeneration in a Mouse Hindlimb Ischemia Model

Peripheral arterial disease affects nearly 202 million individuals worldwide, sometimes leading to non-healing ulcers or limb amputations in severe cases. Genetically modified stem cells offer potential advantages for therapeutically inducing angiogenesis via augmented paracrine release mechanisms a...

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Detalles Bibliográficos
Autores principales: Deveza, Lorenzo, Choi, Jeffrey, Lee, Jerry, Huang, Ngan, Cooke, John, Yang, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893644/
https://www.ncbi.nlm.nih.gov/pubmed/27279910
http://dx.doi.org/10.7150/thno.12866